 |
|
|
|
|
|
|
Article 1 - 5 of 72 |
|
Predictor(TM) hERG Fluorescence Polarization Assay Kit performed on the PHERAstar/PHERAstar Plus
The potential for cardiotoxic side-effects continues to challenge the development of small molecule based therapies. These intolerable side-effects are often precipitated by drug-induced long QT syndrome (LQT), which is often linked to blocking the human ether-a-go-go related gene (hERG) potassium channel. Although patch-clamp electrophysiology remains the gold standard for determining the interaction of compounds with the function of the hERG channel, radioligand displacement assays have proven to be a cost-effective initial alternative assay for hERG channel liability at early stages of compound development....
|
|
Detection of NADH and NADPH with the Omega's High Speed, Full UV/Vis Absorbance Spectrometer
Nicotinamide Adenine Dinucleotide (NAD+), reduced nicotinamide adenine dinucleotide (NADH), nicotinamide adenine dinucleotide phosphate (NADP+) and reduced nicotinamide adenine dinucleotide phosphate (NADPH) have been known to play vital roles in energy metabolism, antioxidation, and reductive biosynthesis. In recent years, these co-factors have been shown to be involved in other physiological functions as well, including aging, oxidative stress, intracellular calcium homeostasis, ROS production, cell death and gene expression....
|
|
"Green Chemstry" in the Laboratory
Using mills as efficient and ecologically friendly synthesis reactors
The term "green chemistry" is commonly used to describe chemical procedures which meet specific requirements with regards to the conservation of resources and protection of the environment. The objective is to avoid undesired by-products by selecting adequate reaction procedures and media. A typical example is the production of bio fuel which has become an ecologically friendly alternative for many drivers....
|
|
Particle Analysis: Quality Control of Catalysts with Digital Image Processing
Catalysts are widely used as an important auxiliary material in the chemical and petrochemical industry. They are able to accelerate chemical reactions by lowering the activation energy, i.e. they change reaction kinetics. Thus, using catalysts in industrial processes has the advantage of higher productivity combined with less energy consumption....
|
|
Polyolefins: Determination of Molecular Weight and Branching Structure by GPC/SEC
Polyethylene and Polypropylene are so-called Polyolefins. They are produced in large amounts every year. Depending on the process and catalyst used linear or branched polymers can be produced. In case of e. g. Polyethylene there are at least three polymer types: HDPE (High Density Polytheylene), LDPE (Low Density Polyethylene) and LLDPE (Linear Low Density Polytehylene). HDPE and LLDPE are made of linear or only slightly branched macromolecules with a high level of crystallinity. They form a dense structure in the final product. LDPE is made of highly branched molecules that form a final structure with low density due to a low degree of crystallinity....
|
|
|
|
|
|
|
|
Top
analytica
analytica China
analytica Vietnam
analytica Anacon